| No. | Item | Definition |
|---|---|---|
| 1. | ado | fuss or difficulty |
| 2. | adversity | hardship or misfortune |
| 3. | affliction | something causing pain or distress |
| 4. | aftermath | the results after bad events |
| 5. | aggravation | something causing irritation or stress |
| 6. | ailment | an illness or physical trouble |
| 7. | annoyance | something that causes irritation |
| 8. | anxiety | worry or nervous trouble |
| 9. | bad patch | a difficult period |
| 10. | bane | a cause of misery or trouble |
| 11. | barrier | something that blocks action |
| 12. | bind | an awkward, difficult situation |
| 13. | bother | annoying difficulty or inconvenience |
| 14. | breakdown | a failure of normal function |
| 15. | burden | a heavy responsibility or difficulty |
| 16. | bust-up | a quarrel or breakup |
| 17. | calamity | a disastrous event or trouble |
| 18. | catastrophe | a terrible disaster |
| 19. | chaos | complete disorder and confusion |
| 20. | complication | something that makes matters harder |
| 21. | conflict | serious disagreement or struggle |
| 22. | confusion | uncertainty or disorder |
| 23. | contention | heated disagreement or conflict |
| 24. | crisis | a time of intense difficulty |
| 25. | debacle | a complete failure or mess |
| 26. | difficulty | a hard or challenging situation |
| 27. | disaster | a sudden great misfortune |
| 28. | discord | lack of agreement or harmony |
| 29. | dispute | a disagreement or argument |
| 30. | disruption | an interruption causing problems |
| 31. | distress | extreme difficulty or suffering |
| 32. | disturbance | a disruption of normal order |
| 33. | emergency | a serious urgent situation |
| 34. | encumbrance | a burden or hindrance |
| 35. | fallout | negative consequences after conflict |
| 36. | fiasco | a complete embarrassing failure |
| 37. | flare-up | a sudden outbreak of trouble |
| 38. | friction | conflict causing difficulty |
| 39. | frustration | annoyance from blocked efforts |
| 40. | fuss | unnecessary excitement or difficulty |
| 41. | glitch | a small unexpected problem |
| 42. | grief | serious annoyance or difficulty |
| 43. | hard time | a period of difficulty |
| 44. | hardship | severe difficulty or suffering |
| 45. | hassle | an annoying difficulty |
| 46. | hazard | a source of danger |
| 47. | headache | a source of difficulty or worry |
| 48. | hindrance | something causing delay or difficulty |
| 49. | hitch | a small problem or delay |
| 50. | hot water | serious difficulty or disfavor |
| 51. | impediment | something that hinders progress |
| 52. | inconvenience | minor difficulty or annoyance |
| 53. | interference | unwanted involvement causing problems |
| 54. | issue | an important problem or concern |
| 55. | jam | a tight or difficult situation |
| 56. | jeopardy | danger of loss or harm |
| 57. | malady | a disease or serious problem |
| 58. | malfunction | a failure to work properly |
| 59. | menace | a threatening danger |
| 60. | mess | a confused or difficult situation |
| 61. | mischief | troublesome behavior or harm |
| 62. | misery | great suffering or discomfort |
| 63. | misfortune | bad luck or trouble |
| 64. | nuisance | something annoying or troublesome |
| 65. | obstacle | something blocking progress |
| 66. | ordeal | a painful or difficult experience |
| 67. | outbreak | a sudden start of disorder |
| 68. | pain | an annoying burden or difficulty |
| 69. | peril | serious danger |
| 70. | pickle | a troublesome situation |
| 71. | plague | a persistent source of annoyance |
| 72. | predicament | a difficult, unpleasant situation |
| 73. | problem | something difficult needing a solution |
| 74. | problematic situation | a situation full of problems |
| 75. | quarrel | an angry argument or dispute |
| 76. | repercussions | unintended bad consequences |
| 77. | risk | possibility of loss or harm |
| 78. | roadblock | something stopping progress |
| 79. | rough going | difficult progress or conditions |
| 80. | rough patch | a difficult period |
| 81. | ruckus | a noisy disturbance or fuss |
| 82. | setback | a problem causing delay |
| 83. | snag | an unexpected problem or obstacle |
| 84. | spot | a difficult situation |
| 85. | sticky situation | an awkward difficult situation |
| 86. | strife | bitter conflict or difficulty |
| 87. | stumbling block | an obstacle to progress |
| 88. | suffering | pain or hardship |
| 89. | threat | a sign of possible harm |
| 90. | tight spot | a difficult situation |
| 91. | torment | severe pain or distress |
| 92. | trial | a difficult test or experience |
| 93. | tribulation | great suffering or difficulty |
| 94. | turmoil | great confusion or disorder |
| 95. | unease | anxious discomfort or concern |
| 96. | uproar | noisy disorder or disturbance |
| 97. | upset | a disturbing problem or setback |
| 98. | vexation | annoyance or distress |
| 99. | woe | great distress or difficulty |
| 100. | worry | a cause of concern |